Research topic of the research group is the development of new instruments and implants for neurovascular applications. For this, the blood flow behavior is investigated with the use of various existing stent implants for the treatment of cerebral aneurysms.
The aim of the AP 1 "pipeline for the reconstruction of vascular models" is the development of a demonstrator for the reconstruction of vessel models in the human brain. An integrated and more automated pipeline that enables rapid modeling even in the case of typical artifacts (merger and flushing artifacts) is to be developed. The pipeline will be thoroughly tested and evaluated in terms of the achieved model quality and the effort and serves as the basis for a simulation of blood flow.
The development of a demonstrator which reads simulation results and makes them clinically useable is the main focus of the AP 2 "Standardized Evaluation CFD". Furthermore, results of the blood flow simulation which are generated using computational fluid dynamics (CFD) are validated . Simulations of novel stent implants are also compared with each other by means of imaging flow experiments.
The generation of realistic blood flow simulations in intracranial aneurysm models for the identification of improved treatments for the patient is the focus of the AP 3 "blood flow simulation and measurement". On the basis of the simulation results, the intervention planning carried out by the relevant doctor can be supported. In this connection, the content of the reality simulation is further enhanced by taking into account patient-specific wall information. It also carries out comparisons with experimental measurements in order to validate the numerical approaches.
The aim of the AP 4 "Thin flexible catheter tubes" is to explore, in cooperation with the Primed Halberstadt Medizintechnik GmbH a catheter tube, which allows to place novel implant forms for the treatment of neurovascular pathologies (e.g., aneurysms, stenoses) in far distal and branched vessels. In the first year , the OVGU defines the clinical and technical parameters in a list of requirements. This includes, inter alia, Vessel wall thickness, diameter, vessel lengths, elasticity, temperatures and coefficient of friction between the catheter and vessel wall. From year 2 to 5, Primed researches the technological process parameters for extrusion of these hoses. In the 5th year, a first demonstrator will be tested by the OVGU. This test includes, inter alia, the characteristics like Torque Ability, pushability and trackability. For this purpose, test stations are developed in accordance with industry standards.
As part of the AP 5 "Non-invasive temperature monitoring" the Acandis GmbH & Co. KG explores the impact and the clinical benefits of an endovascular hypothermia system for the prevention of affected areas of the brain during ischemic stroke. For this purpose, in the first year Acandis develops a “hypothermia phantom” which should adjust the temperature profile processes in the brain in arterial cooling. From year 2 to 5, the temperature spread at Phantom is explored with various systems on the part of OVGU. The aim is to find a technically realizable preferred option for a non-invasive temperature profile control. These include, inter alia, both the testing of a microwave temperature measurement and the determination of the temperature by MRI phase mapping sequences as well as fiber optic temperature measurements.
Contact:
PD Gabor Janiga
Telefon 0391-67-18196
Fax 0391-67-12840
E-Mail
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