The aim of the research group "Clinical Neurology Integration" is to collect requirements for new methods of stroke and aneurysm treatment and the provision of clinical data from the user's perspective. In addition to the developed technical solutions, an iterative clinical evaluation takes place during the entire project, inter alia on the phantom or animal model.
The aim of the AP 1 "Stroke: One Stop Shop" is to establish a holistic approach on the implementation of the diagnostic and therapeutic chain in the treatment of ischemic or hemorrhagic strokes in the angiography laboratory under C-arm imaging. To implement this "one-stop shop" approach, clinical and neuroradiological demands are formulated in the work package, which are included in the work packages of the partner groups then. Using the phantom or animal model, the resulting technological solutions are evaluated in the research group according to the clinical point of view of the experiment. The objectives here are, in particular, the improved soft tissue representation, an increased visibility of vascular implants and a perfusion imaging with a reduced radiation dose.
The AP 2 "Stroke tools" aims at increasing the technical success rate and the proportion of successful stroke therapies for a drastic reduction of the complication rate. To achieve this goal, technical solutions are developed in cooperation with the participating partners that are based on clinical needs and will be evaluated later with clinical expertise. Operating points to achieve this objective are, inter alia, the design of new thrombectomy devices, new methods for non-invasive monitoring of the temperature in the stroke area with local intra-arterial cooling and an improved virtual representation of occluded vessels under angiographic imaging.
In AP 3 "aneurysm diagnosis" the requirements are worked out in a simulation and visualization software for computer-assisted aneurysm characterization and therapy. The clinical focus is on the detection of a rupture criterion, which among other things, is composed of hemodynamic and structural parameters. Furthermore, requirements on new catheter tubes of clinical and technical perspective are explored that enable a broader aneurysm exploration. The solutions developed in cooperation with the technically oriented partner research groups are clinically and iteratively evaluated throughout the development process.
The aim in AP 4 "Aneurysm Tools" is to develop a software demonstration tool throughout the duration of the project in cooperation with the partners of Research Campus STIMULATE, which allows to implement an ideal treatment strategy for the treatment of intracranial aneurysms from patient-specific vascular morphologies. On the clinical side, workflows concerning the aneurysm treatment are being described and a catalogue with different, currently used devices for aneurysm treatment will be compiled and already prepared clinical data will be made available to the technical partners. The final demonstration tool is then evaluated using a phantom study. Furthermore, patient-specific simulated implants are clinically evaluated in the software demonstration tool.
Contact:
Dr. Oliver Beuing
Institut für Neuroradiologie (INR)
Haus 60a, Leipziger Str. 44
39120 Magdeburg
Tel.: 0391-67-21681
Fax: 0391-67-21687
E-Mail
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