In the research group C-arm imaging (NB), the C-arm imaging is being explored with the aim to expand the C-arm to a full imaging modality for stroke diagnosis directly in the surgery room.
The planned one-stop-shop - strategy should save stroke patients the time-consuming transport between surgery room and CT - "Time is brain". Providing a faster treatment, the treatment success rate for the patient can be increased enormously. The time-sensitive nature of a stroke treatment can be guessed by looking at the following numbers: per minute approximately 1.9 million neurons, 14 billion synapses and 12 km are destroyed myelinated nerve fibers in acute ischemic stroke.
The aim of the research group NB is to explore new methods and to implement them (especially 3D / 4D) not only to improve the imaging of the C-arm, but also to reduce the radiation dose for the patient. The main focus of the FG is the investigation of iterative reconstruction methods. For the application of such processingintensive systems the appropriate hardware is used. The implementation is typically based on multi-GPU systems.
The individual work packages follow the imaging requirements which should upgrade the C-arm to a full stroke diagnosis. The increase in "soft tissue contrast resolution", in particular for the illustration of cerebral haemorrhage, is object of AP 1. With the help of various algorithmic improvements, the reduction of image artifacts and the improvement of the contrast-to-noise ratio is targeted.
In AP 2 "reconstruction / dose reduction", novel iterative reconstruction methods are explored that can model both the statistical nature of X-rays as well as their material-specific and energy-dependent absorption characteristics
Subject of the AP 3 "perfusion" is the realization of an effective perfusion, i.e. the reconstruction of the blood flow to the brain tissue. Therefore, knowledge of the contrast agent transport is a priori integrated by appropriate time evolution models into a 4D reconstruction in order to compensate the temporal undersampling of the slowly rotating C-arm.
The aim of the AP 4 "stent radiopacity" is to increase the visibility of different neurovascular implants both in the 2D fluoroscopy as well as in the 3D reconstruction. Together with the research group BV, this is done with hardware in cooperation with the company Acandis by introducing appropriate marker structures into the implants as well as the software side in addition to improved reconstruction methods by image processing algorithms (segmentation, registration, highlighting).
Contact:
Robert Frysch
Gebäude 09-421
39106 Magdeburg
Tel.: 0391-67-51489
Fax.: 0391-67-19347
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