Am Montag, dem 30.11.2015, findet in Gebäude 29, Raum 301 ab 16.00 Uhr das STIMULATE-Kolloquium statt.
Vortragender: Prof. Pádraig Cantillon-Murphy, University College Cork
Thema: "Image-guided interventions for diagnosis and therapy in the airways"
Abstract: Image-guided interventions in non-line-of-sight clinical applications is invariably achieved through electromagnetic tracking. While commercial EM trackers are available, there are issues with noise immunity, magnetic field interference and signal analysis. To address these issues, we have developed an in-house EM tracking platform suitable for pre-clinical investigations and image-guided interventions. A planar magnetic transmitter, is used to generate a low frequency magnetic field distribution which is detected by a small commercial coil sensor. The field transmitter is controlled by a novel closed-loop system that ensures a highly stable magnetic field with reduced interference from one transmitter coil to another. Efficient demodulation schemes using synchronous detection of each magnetic field component experienced by the sensor are employed. The overall tracking accuracy of the system is shown to be less than 2 mm with an orientation error less than 1°. A low cost demodulation implementation using a unique under-sampling approach significantly reduces implementation cost, allowing low-cost manufacture of the system.
The EM tracking system has been combined with lung CT to demonstrate pre-clinical evaluation in a breathing lung phantom. The airways of the phantom are successfully navigated using the system in combination with a 3D computer model rendered from CT data. Registration is achieved
using both a landmark rigid registration method and a hybrid fiducial-free approach. Most recently, the tracking system has been combined with semi-automated navigation to facilitate joystick-controlled catheter steering using image-guidance and EM tracking in the outer airways, where lung cancer is most likely to occur. This approach opens the way for combined image-guided diagnosis and therapy in the outer airways and this is an active area of research for the group.
CV: Pádraig Cantillon-Murphy is currently Lecturer in Electrical and Electronic Engineering at University College Cork, Ireland and an Honorary Lecturer at the Institute of Global Health Innovation, Imperial College London. He graduated with a first-class honours B.E. degree (2003) in Electrical and Electronic Engineering from University College Cork, Ireland before completing his Master of Science (2005) and Ph.D. (2008) degrees at the Department of Electrical Engineering and Computer Science at Massachusetts Institute of Technology (MIT). His doctoral thesis examined the confluence of magnetic resonance imaging (MRI) and magnetic nanoparticle contrast agent dynamics. From 2008 to 2010, he was a postdoctoral research fellow with concurrent appointments at Harvard Medical School, Brigham and Women's Hospital, Boston and at the Research Laboratory of Electronics at MIT. This work examined the role of magnetics in minimally invasive surgical procedures. He is principal investigator at the Biomedical Design research group at UCC which explores novel device development in surgery and endoscopy. The group continues to collaborate with partners in the US and Europe and has won over 1M euro in external funding over the past 5 years. Pádraig’s current research interests include image-guided interventions, electromagnetic navigation, medical device design and surgical robotics. He is module coordinator for the UCC Biomedical Design module, an awarding-winning teaching program which couples medical and engineering students at UCC. He is a former Marie Curie fellow (2010-2014), a former MIT Whitaker fellow (2007-08), and a senior member of the IEEE. His group is currently recruiting mechanical engineering PhD candidates.
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