@article{heinrich_holoinjection:_2019,
	title = {{HoloInjection}: augmented reality support for {CT}-guided spinal needle injections},
	volume = {6},
	issn = {2053-3713 2053-3713 2053-3713},
	doi = {10.1049/htl.2019.0062},
	abstract = {The correct placement of needles is decisive for the success of many minimally-invasive interventions and therapies. These needle insertions are usually only guided by radiological imaging and can benefit from additional navigation support. Augmented reality (AR) is a promising tool to conveniently provide needed information and may thus overcome the limitations of existing approaches. To this end, a prototypical AR application was developed to guide the insertion of needles to spinal targets using the mixed reality glasses Microsoft HoloLens. The system's registration accuracy was attempted to measure and three guidance visualisation concepts were evaluated concerning achievable in-plane and out-of-plane needle orientation errors in a comparison study. Results suggested high registration accuracy and showed that the AR prototype is suitable for reducing out-of-plane orientation errors. Limitations, like comparatively high in-plane orientation errors, effects of the viewing position and missing image slices indicate potential for improvement that needs to be addressed before transferring the application to clinical trials.},
	language = {eng},
	number = {6},
	journal = {Healthcare technology letters},
	author = {Heinrich, Florian and Schwenderling, Luisa and Becker, Mathias and Skalej, Martin and Hansen, Christian},
	month = dec,
	year = {2019},
	pmid = {32038851},
	pmcid = {PMC6942927},
	keywords = {augmented reality, augmented reality support, computerised tomography, CT-guided spinal needle injections, high registration accuracy, holoinjection, image registration, in-plane orientation errors, medical image processing, minimally-invasive interventions, mixed reality glass Microsoft HoloLens, needle insertions, needles, out-of-plane needle orientation errors, out-of-plane orientation errors, Phantoms, radiation therapy, radiological imaging, spinal targets},
	pages = {165--171}
}