@article{roloff_investigation_2013,
	title = {Investigation of the velocity field in a full-scale model of a cerebral aneurysm},
	volume = {43},
	issn = {0142-727X},
	url = {http://www.sciencedirect.com/science/article/pii/S0142727X13001355},
	doi = {https://doi.org/10.1016/j.ijheatfluidflow.2013.06.006},
	abstract = {Due to improved and now widely used imaging methods in clinical surgery practise, detection of unruptured cerebral aneurysms becomes more and more frequent. For the selection and development of a low-risk and highly effective treatment option, the understanding of the involved hemodynamic mechanisms is of great importance. Computational Fluid Dynamics (CFD), in vivo angiographic imaging and in situ experimental investigations of flow behaviour are powerful tools which could deliver the needed information. Hence, the aim of this contribution is to experimentally characterise the flow in a full-scale phantom model of a realistic cerebral aneurysm. The acquired experimental data will then be used for a quantitative validation of companion numerical simulations. The experimental methodology relies on the large-field velocimetry technique PTV (Particle Tracking Velocimetry), processing high speed images of fluorescent tracer particles added to the flow of a blood-mimicking fluid. First, time-resolved planar PTV images were recorded at 4500fps and processed by a complex, in-house algorithm. The resulting trajectories are used to identify Lagrangian flow structures, vortices and recirculation zones in two-dimensional measurement slices within the aneurysm sac. The instantaneous inlet velocity distribution, needed as boundary condition for the numerical simulations, has been measured with the same technique but using a higher frame rate of 20,000fps in order to avoid ambiguous particle assignment. From this velocity distribution, the time-resolved volume flow rate has been also derived. In this manner, a direct comparison between numerical simulations and PTV measurements will be possible in the near future, opening the door for highly accurate computational predictions.},
	journal = {International Journal of Heat and Fluid Flow},
	author = {Roloff, Christoph and Bordás, Róbert and Nickl, Rosa and M, Zsolt and Szaszák, Norbert and Szilárd, Szabó and Thevenin, Dominique},
	year = {2013},
	keywords = {Blood flow, Cerebral aneurysm, Phantom model, PIV, PTV},
	pages = {212 -- 219}
}