by Jens Ricke, Oliver S. Großer, Holger Amthauer
Abstract:
We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.
Reference:
Y90-radioembolization of lung metastases via the bronchial artery: a report of 2 cases (Jens Ricke, Oliver S. Großer, Holger Amthauer), In CardioVascular and Interventional Radiology, volume 36, 2013.
Bibtex Entry:
@article{ricke_y90-radioembolization_2013,
	title = {Y90-radioembolization of lung metastases via the bronchial artery: a report of 2 cases},
	volume = {36},
	doi = {10.1007/s00270-013-0690-3},
	abstract = {We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.},
	number = {6},
	journal = {CardioVascular and Interventional Radiology},
	author = {Ricke, Jens and Großer, Oliver S. and Amthauer, Holger},
	year = {2013},
	pages = {1664--9}
}